Queensland's Indigenous community is mourning the loss of one of its most respected leaders.

Aunty Beryl Wharton, who was born in Cherbourg west of Gympie, has passed away after a long illness.

Aboriginal and Torres Strait Islander Commission (ATSIC) commissioner Robbie Williams says Aunty Beryl was known for her compassion and leadership on a range of issues, including Indigenous health.

"She was very involved in a number of community organisations that made contact with families, not only within the south-east Queensland area, but all throughout Queensland; but specifically in her own back yard and she looked after the people ... the larger families especially that were in need of help," he said.

A memorial service commemorating the contribution of Aunty Beryl Wharton is expected to be held early next week.